Children's National Medical Center. Cristian Bale. Pranav Kumar Prabhakar. Reka Kutasi. FaAd MohamEd. Stacy Smith. Youssef Khalfa. More From leovss Isi Pakistan. Shahrukh Farhan. Symbiotic Hydrogenase Activity in Bradyrhizobium Sp. Popular in Biology. Pabitra Saha. Yanuar Dwi Putra. Gungun Yadav. Nazrina Azlan. Nurul Azuwin. Carlos Yong. Nicolas Baron. Guille Paz. Mike zombie. Ripesh Kumar. Danny Garcia. Dimitri Erotico. Katy A. Cancer Foye's Principles of Medicinal Chemistry Anton Cloete.
CarLos RodriGuez. John Osborne. Isak Isak Isak. CBCP for Life. Fajar Yuniftiadi. Evets Desouza. The double-helical structure, held together by specific pairing between the bases on the two strands, has become one of the iconic images of science. The image of the microscope was perhaps the icon of science in the late 19th century, displaced by the mid 20th century by the graphical representation of the atom with its orbiting electrons.
But by the end of the century that image had in turn given way to the double helix. The field of molecular biology as we understand it today was born out of the discovery of theDNAstructure and the agenda for research that that structure immediately provided.
By the time the first edition of Molecular Biology of the Gene was published, just 12 years later in , it had been confirmed that DNA replicated in the manner suggested by the model, the genetic code had all but been cracked, and the mechanism by which genes are expressed, and how that expression is regulated, had been established at least in outline.
The field of molecular biology was ripe for its first textbook, defining for the first time the curriculum for undergraduate courses in this topic.
Our understanding of the mechanisms underlying these processes has hugely increased over the last 48 years since that first edition, often driven by technological advances, including DNA sequencing another anniversary this year is the 10th anniversary of completion of the human genome project. The current edition of Molecular Biology of the Gene celebrates both the central intellectual framework of the field put in place in that first edition and the extraordinary mechanistic, biological, and evolutionary understanding that has since been achieved.
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